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Kinase Drug Discovery (Rsc Drug Discovery)

by Richard A. Ward, Frederick Goldberg, David P. Rotella and David E. Thurston

KinaseInhBoook


Available in Dec 2011.

Visit our bookshelf for more books on Kinases and Kinase Inhibitors or pre-order this book today




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  • Journal articles and patents: 7,035
  • Number of Biological Activity Data Points: >505,000
  • Number of unique kinase molecules with annotated assay data: >191,000
  • Number of all unique kinase molecules from patents and articles (with or without bio-activity data): >536,000
  • Number of unique kinase targets with assay data: 441
  • Number of annotated assay protocols: 22,633
  • Number of annotated chemical reactions: 2,365

The following citations are just a few of the comprehensive list of all SAR data points for each target, computational scientists will find Eidogen-Sertanty's knowledgebase to be an exceptional source for high quality training sets to build predictive QSAR models. All SAR data undergoes rigorous quality control.


Citation Number of
SAR
Data Points
Number
of
Targets
Nat. Biotechnol. 2008 26 127-132
5244 118

1938 51

1938 45

1862 45

1064 28
Nat. Biotechnol. 2005 23 329-336
700 112
Proc. Natl. Acad. Sci. USA 2007, 51, 20523-20528
414 92
J. Med. Chem. 2008 51 7898-7914
84 72
Biochem. J. 2000 351 95-105
621 35
J. Med. Chem. 2005 48 710-722
752 16
Bioorg. Med. Chem. 2008 16 5514-5528
53 4
Leukemia 2009 23 477-485
65 43
Trends Pharmacol. Sci. 2004 25 471-480
54 4
J. Mol. Graph. Model 2007 26 236-245
160 3
Cancer Res. 2005 65 5399-5407
13 3
Med. Chem. 2007 3 75-84
172 2
Chem. Biol. 2005 12 621-637
14 4
Eur. J. Pharmacol. 2007 562 1-11
24 3
J. Mol. Graph Model. 2009 27 642-54
89 1
Bioorg. Med. Chem. 2007 15 4256-64
19 1
J. Med. Chem. 2009 52 4466-80
100 9
AAPS J. 2006 8 E204-21
80 6
Cancer Res. 2008 68 4774-82
17 13
Blood 2009 114 2984-2992
125 41

152 46

182 44

128 25

236 88

294 87
Bioorg Med Chem Lett. 2009 19 6691-6695
363 6
J Med Chem. 2009 52 8010-8024
222 10
Nat Rev Cancer. 2009 9 28-39
12 12
Bioorg Med Chem. 2009 17 6728-6737
204 8
Bioorg Med Chem Lett. 2010 20 334-337
78 52
Bioorg Med Chem Lett. 2009 19 5887-5892
146 3
Bioorg Med Chem Lett. 2010 20 2033-2037
49 3

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